Immune privilege or privileged immunity?
نویسندگان
چکیده
منابع مشابه
The privileged immunity of immune privileged organs: the case of the eye
Understanding of ocular diseases and the search for their cure have been based on the common assumption that the eye is an immune privileged site, and the consequent conclusion that entry of immune cells to this organ is forbidden. Accordingly, it was assumed that when immune cell entry does occur, this reflects an undesired outcome of breached barriers. However, studies spanning more than a de...
متن کاملImmune Privilege
T he concept of immune privilege refers to the observation that tissue grafts placed in certain anatomical sites, including the brain and eye, can survive for extended periods of time (1). Immune privilege is thought to reflect an evolutionary adaptation to protect vital structures from damage by inflammatory responses directed against pathogens. It was originally believed that antigens in immu...
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As typically conceived, the goal of information retrieval is to help people find what they seek. However, when sensitive content is intermixed with what is sought, it can be equally important to help protect what should not be seen. This paper focuses on one such case, the protection of content that is subject to a claim of attorney-client privilege when sharing evidence incident to civil litig...
متن کاملOcular immune privilege
The eye attempts to limit local immune and inflammatory responses to preserve vision. This phenomenon, known as ocular immune privilege, is mediated by a combination of local and systemic mechanisms. While immune privilege is believed to protect the eye from day-to-day inflammatory insults, it is not absolute and its mechanisms are still incompletely understood.
متن کاملMechanism of Immune Privilege
The eye is a privileged site that cannot tolerate destructive inflammatory responses. Inflammatory cells entering the anterior chamber of the eye in response to viral infection underwent apoptosis that was dependent on Fas (CD95)-Fas ligand (FasL) and produced no tissue damage. In contrast, viral infection in gid mice, which lack functional FasL, resulted in an inflammation and invasion of ocul...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2008
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2008.27